SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69d25f770b3f04e0780232d953aaada8461ec429b836d52c949adca01d8c5f21' 
  AND token = 'jOhlVx1vgtUUfHmhW8D6hlOG2DuQT0VJfwpJgVcr4mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}