SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7321a8e7307e1c2fe99762d83a07a0c1e66debe50ab2e4d2ca4ab1f71298875' 
  AND token = 'xqma9cSnETh1NvI5zQv6MyTun1SJ/7K9ICP1Fcfha54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}