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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a78bff634001f24653c37eac598b424756b6f8a0ea70a1ea19f9f09486a7a6bb' 
  AND token = 'oVBAuOkYFepnrz613L+otA38bciWljWydXFllEirwNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}