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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f3dafccfefdbeb36d6ef4f1762d7d4a5453b50e053e2f9b9a191ad3ed630b2' 
  AND token = 'cGMY6Vxa30CkGNt3CX1vX4UPZ2CNjMU1mRaHi5x6x3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}