SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9100e1a9d4be2fa4011e7119b0aff97b6ff2c5cba15a4a983941d7cf39506c46' 
  AND token = 'Wpi9AAbfXhhauW1bsD1cu73qckaiqrT+Ds9QZeDTSZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}