SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14436770256ee12084292942db096d33a4c60a57e75d0f682321d930803a213b' 
  AND token = 'gkTJCwGYZnCV9W2Y1TI1YFN6AngC0e945xu9kCHgg8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}