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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25c5d579d358ecdb1160b350dfa4c4878dd838b32663574484f9e34d2e4de418' 
  AND token = 'ZJTuIMJf2WiuDmr3JUxB0joMz96t/X6AFZWuLnwo7QE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}