SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3273d199b82810ef58e4d47c4a38b325e9b2e901478ce40a5617ddbe534bd61' 
  AND token = 'AzYBJ0+7sAoEIHhlbJszoRypLmfe2W//yLSNmHG/y10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}