SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f01273a0b4ec22e296c45dfef2f13ea2b8b4d8a278f35feca8608887628a748e' 
  AND token = 'zF3aik4WepKHoiGJD7JN65W+NYQnWa/0OMeKyn4Qcks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}