SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cdc2132ae4bd320bd359791e556b59f00fa6122559f31d8f27fb98cb6885e7a' 
  AND token = 'vS+/LbqPh9DHWZaiI/MjudTpBFX+C1mbdZH915F9G88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}