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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aadb4490293588a2cd2d457946f9efe772e58ce378ade8affc0b34d5070dc78' 
  AND token = 'UZ++rofQkoqgzhTwqQbXu/fM2LMMMhKgiUW0Lo24+GQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}