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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1324f540cd7e738266558fb75e4ba2c4bbb5cfcfee08be1a4b77898dadac2840' 
  AND token = 'KqaULdBs+I0S40c3vEyA9WYctojQU8PsE78wCaz7UEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}