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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8afda1fb41cf5162dd73bfa86e5516a335f1a6f59d942ffdbd3cc40d0e854180' 
  AND token = 'cdzcLIHzBsYT9W/0OcKkTlG2An/uVo7BMlRDXl3+2Dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}