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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2c06e32781da5f6ea1349bc434a2a47e1ad2d7f0df08bab968b4c17401927c' 
  AND token = 'neNVDFPYqIZqA83QNSn+VHv+eGYRcQOBysTvASkhbQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}