SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27d0e6adb6eedc6acf56ca5d303442777cc90c2f93421a4c5ee07b358af21eb1' 
  AND token = 'gBuYE0e9DZbxPpaky4yAbV8CWIxRswzXKXyEOm1C9S8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}