SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c921e3a3eb7ed7c9d31a758e18f96099bda929eae5df71f08b5413eaf65b80b5' 
  AND token = 'FUqp4/NGUROW7u8jPyEHCRW9jD7tMLghCxzJTn6c6bA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}