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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eacac83c9a3d04ca40e8159922dca2846e31a41d07e311b918abd51c258282e' 
  AND token = 'PXWrMjo22j+hFxUuY9b1BoLco0y8qytwoO40M4nwtp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}