SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d33eb049caedcf2252016ed0809e9fa26c24a5c05e3c13921045eaf5d2c5fda' 
  AND token = '0QAECVrc75LrbjImsNZENYt1/MpZiyQsa8gsjGq67fA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}