SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e0c637a94a8320de522f6eb15c13bf8eaea9e3f2ca5b420ef1d96292adf7a4' 
  AND token = 'JCT9qxzSSJafZzw5TcZwr0WZ4BFApIFDSJB2xAzUAFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}