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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ab011dd2915c0741292c07a7ac47998dc53a3c994248c86128130876b24ac5e' 
  AND token = '+38zy6RUZZATKwXqKgRs8MW/ai0uM+pJh1tlVMa7Ebo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}