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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f88526d701786d2c64454603bb7de3dae4fc8158dec8b2baf0c381622925cafd' 
  AND token = 'MKdD+v3QGq2oxCxRLtCS0sRitHU4RwSb1xr5Tw4YNFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}