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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eb38b25d1373988be044c821cc567fcf62b494a8a750d367858f29382b00d80' 
  AND token = 'Zty/zis3Ck4ldKd6MategMoOKMfvRlyLokh47JE5dgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}