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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b89400907a0e778a5bd83c1a2608375f1a68116effe197dd78e7387a8e9dfd3' 
  AND token = 't+mw2sBf5qwxmMHkkk1Z2X527vZLVbxA9okUKZDQap4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}