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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e6ba9883ecec919bd5375ca7ec7c5d94ebcf5a0188143922c6859976005922' 
  AND token = 'AtBi/+W51exS9tjaac+AcyNOb7HzQwCBJhAurXQUBt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}