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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b0a93ba5279d4c3f14010a1f8ad60a89991704eda991808f8d1ec4dda15217' 
  AND token = '0Ip+ekPMSoobqKq0QgCbKY7vFgGrbIsOZH+qgycW/Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}