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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d313c5de8881690fb0cf77edfea81d8e1eea131f0822e493ec9f1eecb3021e9' 
  AND token = '2tlyZTMYEWhSfrprrvb8RHW41piCqAtzOG1GbnJ7vHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}