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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6504df320b858e8fbfeca87ec95eba3aa043d0cd50326d031400b5379f6160fa' 
  AND token = 'CaSaKSP9wi6R+p5OJyP4l138sm1pisy7FNGpb00vJL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}