SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f70e76b3e150f541da6ab8cdf013ccae10a5b008bb16776d338e589a0d36080' 
  AND token = 'Rv3nUjvsLRAh50YESHewOsI60VN3B3ptm+sdvqLKGsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}