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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1104462115487168543803255855a39363ca77039fc3edb48ce600d72389002' 
  AND token = 'W9jobqaZ/zwZk7V5dNTpyw4bQCJVIM06TS3q1SZsXxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}