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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a5dc741a101ea015086b255f72d5d574890db203072893d052bc347e81d1a9c' 
  AND token = 'U9O23Z6ua1sLyLvJw6A2uhsh6SS6UfpEd+imXfFbWKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}