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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2a1e919da2aa39660b9b2fd188e0cb84cc498e27088d56ecf7b39a62d51fc0b' 
  AND token = 'vyPmcdV57uetWWvgGZM5jsSgA/ozkQ7v1V1AvYdeydU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}