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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74a03a7a4c5dced7f65f21901b662374a79793318ef6f3497a7977344e70b29c' 
  AND token = 'AbAEfbT+1MYUmqz9++OpWiE/EnX52ouNvTrVGCnTUU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}