SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '289b5de0dc9a77a5a93533deb7c1b9f4095253e3608ce9d80a76c07953c814fd' 
  AND token = 'NTQJSfNisl65jlCm4DMEuoOa2OtqWxsOBjUzX9BibOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}