SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a3a8a48cc9f59ef806357a2dcc03758ba02cebda58c8ba5f278a32c7d8e03a9' 
  AND token = '/TGHNiqJkCMh1y0wxkaqWdvrO8maq2v712AEmtznhtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}