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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4d8daa38eaf336f251d9a8c8b8cb8941fd2f8b849a0beee9684873021b5339f' 
  AND token = 'RNcc0qXHKAqTSpGl2+CkpafIYkT2dJyQr/XmhA/g/EU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}