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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7788023267a48004065a260a2606b1e330238c80906b2de36a68261d1bec82e' 
  AND token = 'ESfbps6rGW/AuCp5b6hGevU4pgTX7hmbocgbq7DPBvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}