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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dee1f54e6b73c46a9866e34c4edcfdb5d1f8161b9a6a353df262f9b1f801ca6' 
  AND token = 'zOo36vB/GzPueE2pLMiupUqCM79sqgqstdglWSjxL68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}