SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a49a92c518092a1f491dfe3e79bd43d09e6bf0defc7b8a0942763aad9c670aa9' 
  AND token = 'zLguVij6PYzCkPNOnLwq2h184cgd6ljB/63UUr6z1ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}