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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dad72049ecf2d6298ab42c475905e9dffea1cdfd38d176c21c30614b37d43e51' 
  AND token = 'xmP4GeUIiT/DYdHLHw2TJFMTxGNEhFpo94gON2a8da4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}