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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '847509d7d49a0608a856bd1209aa41ec34ca51c182182d56900c6dba18e7013b' 
  AND token = 'AHE+im+NJB5TpCEcDCzgPhOZsKnU2qU2z6EM7kIlaSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}