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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b18d5ab53771b79dd9d764db6e48b7cb6eb5d23adcdac61e7d4c2984d31a7e0' 
  AND token = '+ZCyekW6aPsmuzpIJRtUNp75MzoFaEfxzQVA+6mz+rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}