SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16522b019f4671ad330a4cfda7787c7d2c6c3dd9b0b3aad8089888355affd045' 
  AND token = 'zkhK5xmC6yP1YJK1nqS7r7/shpTfi0DynrPM8xfOBSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}