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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e83a47699af76acf9f69c3a649fa1dfd54a0e11d9354dfd67af014e9c4299d' 
  AND token = '67P0QB48ktyb/bMiIpEX7G4NTAkdA9ehVtmuSNAQVdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}