SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd933a9045f111bf80260e72c82ce77e3456c8448e5d4d7c7fca764b6b4c1864d' 
  AND token = 'eZetitirHVaN1hNEE0jv/SbZukw3nlIdsOZrfnS3SxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}