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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1ddd95b41bc3889ebbd9945f50571d3f7435d142953841017eaba7e59f392c6' 
  AND token = 'DGTLzwCSHaH9vy+vNf9d8sY9Lr85NVW32DxUkSm5yaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}