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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b18d25ef7ce1c83adf0842df2f2e4d99d43da2ee65932009f5aa75f3b301df0' 
  AND token = 'M3U80P+R6G7PLxJGxb8T6DLGltdQXdDPKqV5fmbGCls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}