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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7926cbe81150acea7cdbfb7c8a7e264113ebf1180952c607beb828e760fb46a5' 
  AND token = '/oIxG4S/A3+wFJnSEFvyPKWOQR5E55oBYs+ADjKSv1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}