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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b1ae1328776fc021fcd5494792cda03b8c1fc3e3b9f916531be0c52d177f81d' 
  AND token = 'bqzU3ud67tzdmZVnbtmjmq2RNrT/L7Pgi5mGrPZFmlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}