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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dda2852bd3d9be86ecca5118dd1e70cceb80cb27f0fb972e5a38eff23ff6736' 
  AND token = 'djoApVgAlHUwQcVjAypNG4m/ktaLZxBRMhIoDAO2VMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}