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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '487085e31ab06d9807107dbecc0d16c5c8582a2be565a896fe2b21a70f6cf1c8' 
  AND token = 'UgfTVPLQAGNXyEGw/YCGOrcz1h+kGfkTtkrhB6ZqbOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}